Journal article

Authors list: Zorn, H; Fischer-Zorn, M; Berger, RG

Publication year: 2003

Pages: 367-372

Journal: Applied and Environmental Microbiology

Volume number: 69

Issue number: 1

ISSN: 0099-2240

DOI Link: https://doi.org/10.1128/AEM.69.1.367-372.2003

Publisher: American Society for Microbiology

Abstract: 
Submerged cells of the basidiomycete Nidula niveo-tomentosa, a microbial producer of 4-(4-hydroxyphenyl)-butan-2-one, were supplemented with C-13-labeled L-phenylalanines and with [1-C-13] glucose. Labeled transformation products were detected by a novel method of analyzing stable isotope-labeled metabolites, gas chromatography (GC) coupled to an atomic emission detector, and by GC-mass spectrometry. A benzoate moiety was side chain elongated according to the poly-beta-keto scheme. The presence of an acetyl coenzyme A-carboxylase inhibitor shifted the spectrum of products to benzyl compounds. Hence, the fungal pathway differs from the one established for plant tissues.

Harvard Citation style: Zorn, H., Fischer-Zorn, M. and Berger, R. (2003) A Labeling study to elucidate the biosynthesis of 4-(4-hydroxyphenyl)-butan-2-one (raspberry ketone) by Nidula niveo-tomentosa, Applied and Environmental Microbiology, 69(1), pp. 367-372. https://doi.org/10.1128/AEM.69.1.367-372.2003

APA Citation style: Zorn, H., Fischer-Zorn, M., & Berger, R. (2003). A Labeling study to elucidate the biosynthesis of 4-(4-hydroxyphenyl)-butan-2-one (raspberry ketone) by Nidula niveo-tomentosa. Applied and Environmental Microbiology. 69(1), 367-372. https://doi.org/10.1128/AEM.69.1.367-372.2003