Journal article

Authors list: Meyer, F; Goesmann, A; McHardy, AC; Bartels, D; Bekel, T; Clausen, J; Kalinowski, J; Linke, B; Rupp, O; Giegerich, R; Pühler, A

Publication year: 2003

Pages: 2187-2195

Journal: Nucleic Acids Research

Volume number: 31

Issue number: 8

ISSN: 0305-1048

eISSN: 1362-4962

DOI Link: https://doi.org/10.1093/nar/gkg312

Publisher: Oxford University Press

Abstract: 
The flood of sequence data resulting from the large number of current genome projects has increased the need for a flexible, open source genome annotation system, which so far has not existed. To account for the individual needs of different projects, such a system should be modular and easily extensible. We present a genome annotation system for prokaryote genomes, which is well tested and readily adaptable to different tasks. The modular system was developed using an object-oriented approach, and it relies on a relational database backend. Using a well defined application programmers interface (API), the system can be linked easily to other systems. GenDB supports manual as well as automatic annotation strategies. The software currently is in use in more than a dozen microbial genome annotation projects. In addition to its use as a production genome annotation system, it can be employed as a flexible framework for the large-scale evaluation of different annotation strategies. The system is open source.

Harvard Citation style: Meyer, F., Goesmann, A., McHardy, A., Bartels, D., Bekel, T., Clausen, J., et al. (2003) GenDB - an open source genome annotation system for prokaryote genomes, Nucleic Acids Research, 31(8), pp. 2187-2195. https://doi.org/10.1093/nar/gkg312

APA Citation style: Meyer, F., Goesmann, A., McHardy, A., Bartels, D., Bekel, T., Clausen, J., Kalinowski, J., Linke, B., Rupp, O., Giegerich, R., & Pühler, A. (2003). GenDB - an open source genome annotation system for prokaryote genomes. Nucleic Acids Research. 31(8), 2187-2195. https://doi.org/10.1093/nar/gkg312