Journal article

Authors list: Laber, Lars; Jandowsky, Anabell; Frölich, Kai; Heinrich, Andre P; Düring, Rolf-Alexander; Donath, Tobias W; Eichberg, Carsten

Publication year: 2023

Journal: Science of the Total Environment

Volume number: 905

ISSN: 0048-9697

eISSN: 1879-1026

Open access status: Hybrid

DOI Link: https://doi.org/10.1016/j.scitotenv.2023.167152

Publisher: Elsevier

Abstract: 
Sheep function as effective endozoochorous seed vectors in grasslands. Recent laboratory-based studies showed that this important function can be impaired by macrocyclic lactone anthelmintics, which are used to control parasites and enter into the environment mainly via faeces; however, there is a lack of in vivo studies. We conducted a seed-feeding experiment with sheep that included four temperate grassland species from four different families (Achillea ptarmica, Asteraceae; Agrostis capillaris, Poaceae; Dianthus deltoides, Caryophyllaceae; Plantago lanceolata, Plantaginaceae). A series of three feeding trials was carried out after one of two groups of sheep received a single administration of a common oral formulation of the macrocyclic lactone moxidectin. Faeces were collected to determine seedling emergence rate and emergence timing as well as moxidectin concentration via HPLC. Seedling emergence differed significantly between the anthelmintic-treated sheep and the control group. This impact depended on time of seed uptake after anthelmintic administration. Number of emerging seedlings was significantly reduced (27.1 %) when faeces moxidectin concentrations were high (on average 3153 ng g(-1); 1 d post treatment) and significantly increased (up to 68.8 %) when moxidectin concentrations were low (<= 86 ng g(-1); 7, 14 d pt). Mean emergence time was significantly lowered at low moxidectin concentrations. These results demonstrate dose-related effects of deworming on seedling emergence which might affect endozoochory and eventually plant population dynamics in grasslands.

Harvard Citation style: Laber, L., Jandowsky, A., Frölich, K., Heinrich, A., Düring, R., Donath, T., et al. (2023) Dose-dependent in vivo effects of formulated moxidectin on seedling emergence of temperate grassland species, Science of the Total Environment, 905, Article 167152. https://doi.org/10.1016/j.scitotenv.2023.167152

APA Citation style: Laber, L., Jandowsky, A., Frölich, K., Heinrich, A., Düring, R., Donath, T., & Eichberg, C. (2023). Dose-dependent in vivo effects of formulated moxidectin on seedling emergence of temperate grassland species. Science of the Total Environment. 905, Article 167152. https://doi.org/10.1016/j.scitotenv.2023.167152