Journal article

Authors list: Kolodziej, Malgorzata; Uhl, Eberhard; Schwarm, Frank; Nagl, Jasmin; Schuerg, Rainer; Meinhold-Heerlein, Ivo; Tinneberg, Hans-Rudolf

Publication year: 2020

Pages: 1151-1157

Journal: Neuromodulation: Technology at the Neural Interface

Volume number: 23

Issue number: 8

ISSN: 1094-7159

eISSN: 1525-1403

DOI Link: https://doi.org/10.1111/ner.13157

Publisher: Wiley

Abstract: 

Objective The aim of this study was to report on the use of laparoscopic implantation of leads on the branches of the sacral plexus for neuromodulation in the treatment of chronic pelvic pain (CPP) in a multidisciplinary setting with the help of electrophysiological neuromonitoring.

Materials and Methods Between 2012 and 2019, six female patients complaining of chronic pain and bladder and bowel dysfunctions underwent laparoscopic exposure and nerve identification with the help of electrophysiological neuromonitoring. A lead was placed laparoscopically in direct contact with the affected nerve. Pain intensity (numerous ranking scale [NRS]), generic health status (EQ-5D-5L), Becks Depressions Inventory (BDI-V), Pain Catastrophizing Scale (PCS), and Client Satisfaction Questionnaire (CSQ-8) were assessed pre-/postoperatively as well as three and six months after surgery. Statistical analysis was performed using Mann-Whitney U and Wilcoxon rank-sum test.

Results The median age was 36.5 years. NRS improved from a median of 9.5 preoperatively to 3.0 (p < 0.001) at six-month follow-up. Median EQ-5D-5L index value before treatment was 0.18, indicating a notably lowered quality of life and increased up to 0.83 after six months (p < 0.001). Preoperative median BDI-V scores indicated a major depressive mood and improved from a median of 46.0 to 12.0 after six months (p = 0.007). Preoperative PCS was elevated with a median score of 41.0 and decreased to 4.0 after six months (p < 0.001). CSQ showed that patients were satisfied with the treatment.

Conclusions This unique method is an alternative and effective treatment option for CPP even years after primary endometriosis surgery.

Harvard Citation style: Kolodziej, M., Uhl, E., Schwarm, F., Nagl, J., Schuerg, R., Meinhold-Heerlein, I., et al. (2020) Interdisciplinary Laparoscopic Implantation of Neuromodulation Leads to the Sacral Plexus for Therapy of Chronic Pelvic Pain and Neurogenic Bladder Dysfunctions, Neuromodulation: Technology at the Neural Interface, 23(8), pp. 1151-1157. https://doi.org/10.1111/ner.13157

APA Citation style: Kolodziej, M., Uhl, E., Schwarm, F., Nagl, J., Schuerg, R., Meinhold-Heerlein, I., & Tinneberg, H. (2020). Interdisciplinary Laparoscopic Implantation of Neuromodulation Leads to the Sacral Plexus for Therapy of Chronic Pelvic Pain and Neurogenic Bladder Dysfunctions. Neuromodulation: Technology at the Neural Interface. 23(8), 1151-1157. https://doi.org/10.1111/ner.13157