Journal article

Publication year: 2002

Pages: 115-117

Journal: Archiv für Lebensmittelhygiene

Volume number: 53

Issue number: 5

ISSN: 0003-925X

Publisher: Schlütersche Verlagsgesellschaft

Abstract: 
Zeranol (alpha-Zearalanol) is an anabolic agent banned in the European Union. However, recent findings suggest that zearalenone, a natural occurring Fusarium spp. toxin, could be partly reduced to alpha- and its epimer beta-zearalanol by ruminants. Therefore the appearance of this and other zearalenone metabolites in German cattle was investigated by analysing bile. An enzyme immunoassay was used as screen-ing assay, positive samples were purified by immunoaffinity chromatography and analyzed by GC-MS. Zearalenone or zearalenone- derivatives were present in 97 out of 108 bile samples analyzed. The predominant metabolite was P-zearalenol with an average of 93.6 % of the total content of zearalenone metabolites; the highest concentration detected was 1890 ng/ml. alpha-Zearalanol was found in 16 samples with concentrations up to 1.3 ng/ml. While treatment with RALGRO(R), an alpha-zearalanol containing implant, was not suspected this should be the first indication of a natural occurrence of this growth promoting agent in domestic animals in Germany.

Harvard Citation style: Meyer, K., Usleber, E., Dietrich, R., Märtlbauer, E. and Bauer, J. (2002) Zearalenone metabolites in bovine bile, Archiv für Lebensmittelhygiene, 53(5), pp. 115-117

APA Citation style: Meyer, K., Usleber, E., Dietrich, R., Märtlbauer, E., & Bauer, J. (2002). Zearalenone metabolites in bovine bile. Archiv für Lebensmittelhygiene. 53(5), 115-117.