Journal article

Authors list: Seitz, A; Wende, RC; Schreiner, PR

Publication year: 2023

Journal: Chemistry - A European Journal

Volume number: 29

Issue number: 18

ISSN: 0947-6539

eISSN: 1521-3765

Open access status: Hybrid

DOI Link: https://doi.org/10.1002/chem.202203002

Publisher: Wiley

Abstract: 
We report the site-selective acetylation of partially protected monosaccharides using immobilized oligopeptide catalysts, which are readily accessible via solid-phase peptide synthesis. The catalysts are able to invert the intrinsic selectivity, which was determined using N-methylimidazole, for a variety of pyranosides. We demonstrate that the catalysts are stable for multiple reaction cycles and can be easily reused after separation from the reaction solution. The catalysts can also be used in flow without loss of reactivity and selectivity.

Harvard Citation style: Seitz, A., Wende, R. and Schreiner, P. (2023) Site-Selective Acylation of Pyranosides with Immobilized Oligopeptide Catalysts in Flow, Chemistry - A European Journal, 29(18), Article e202203002. https://doi.org/10.1002/chem.202203002

APA Citation style: Seitz, A., Wende, R., & Schreiner, P. (2023). Site-Selective Acylation of Pyranosides with Immobilized Oligopeptide Catalysts in Flow. Chemistry - A European Journal. 29(18), Article e202203002. https://doi.org/10.1002/chem.202203002