Journalartikel

Autorenliste: Haller, O; Kochs, G; Weber, F

Jahr der Veröffentlichung: 2006

Seiten: 119-130

Zeitschrift: Virology

Bandnummer: 344

Heftnummer: 1

ISSN: 0042-6822

DOI Link: https://doi.org/10.1016/j.virol.2005.09.024

Verlag: Elsevier

Abstract: 

Type I interferons (IFN-α/β) are potent antiviral cytokines and modulators of the adaptive immune system. They are induced by viral infection or by double-stranded RNA (dsRNA), a by-product of viral replication, and lead to the production of a broad range of antiviral proteins and immunoactive cytokines. Viruses, in turn, have evolved multiple strategies to counter the IFN system which would otherwise stop virus growth early in infection. Here we discuss the current view on the balancing act between virus-induced IFN responses and the viral counterplayers.

Harvard-Zitierstil: Haller, O., Kochs, G. and Weber, F. (2006) The interferon response circuit: Induction and suppression by pathogenic viruses, Virology, 344(1), pp. 119-130. https://doi.org/10.1016/j.virol.2005.09.024

APA-Zitierstil: Haller, O., Kochs, G., & Weber, F. (2006). The interferon response circuit: Induction and suppression by pathogenic viruses. Virology. 344(1), 119-130. https://doi.org/10.1016/j.virol.2005.09.024