Journal article

Authors list: Weber, F

Publication year: 2007

Pages: 4818-4823

Journal: World Journal of Gastroenterology

Volume number: 13

Issue number: 36

ISSN: 1007-9327

eISSN: 2219-2840

DOI Link: https://doi.org/10.3748/wjg.v13.i36.4818

URL: https://www.wjgnet.com/1007-9327/full/v13/i36/4818.htm

Publisher: Baishideng Publishing Group

Abstract: 

Hepatitis C virus (HCV) needs to tightly manipulate host defences in order to establish infection. The innate immune response slows down viral replication by activating cytokines such as the type I interferons (IFN-alpha/beta), which trigger the synthesis of antiviral proteins and modulate the adaptive immune system. HCV has therefore developed a number of countermeasures to stay ahead of the IFN system. Here, I will attempt to summarize the current state of research regarding IFN responses against HCV and the viral escape strategies. Particular emphasis will be put on the newly discovered mechanisms HCV employs to avoid the induction of IFN in infected cells.

Harvard Citation style: Weber, F. (2007) Interaction of hepatitis C virus with the type I interferon system, World Journal of Gastroenterology, 13(36), pp. 4818-4823. https://doi.org/10.3748/wjg.v13.i36.4818

APA Citation style: Weber, F. (2007). Interaction of hepatitis C virus with the type I interferon system. World Journal of Gastroenterology. 13(36), 4818-4823. https://doi.org/10.3748/wjg.v13.i36.4818