Journalartikel

Anticancer activity of a series of copper(II) complexes with tripodal ligands


AutorenlisteJopp, M; Becker, J; Becker, S; Miska, A; Gandin, V; Marzano, C; Schindler, S

Jahr der Veröffentlichung2017

Seiten274-281

ZeitschriftEuropean Journal of Medicinal Chemistry

Bandnummer132

ISSN0223-5234

DOI Linkhttps://doi.org/10.1016/j.ejmech.2017.03.019

VerlagElsevier


Abstract
A series of copper(II) complexes with tripodal polypyridylamine ligands (derived from the parent ligand tris(2-pyridylmethyl)amine, tmpa) has been synthesized. Crystallographic characterization was possible for all complexes obtained. The copper(II) chloride complexes were investigated for their in vitro anticancer potential using human tumor cell lines containing examples of cervical, colon, ovarian cancers and melanoma. Some compounds showed a similar activity compared to that of cisplatin, however no systematic behavior could be observed.



Zitierstile

Harvard-ZitierstilJopp, M., Becker, J., Becker, S., Miska, A., Gandin, V., Marzano, C., et al. (2017) Anticancer activity of a series of copper(II) complexes with tripodal ligands, European Journal of Medicinal Chemistry, 132, pp. 274-281. https://doi.org/10.1016/j.ejmech.2017.03.019

APA-ZitierstilJopp, M., Becker, J., Becker, S., Miska, A., Gandin, V., Marzano, C., & Schindler, S. (2017). Anticancer activity of a series of copper(II) complexes with tripodal ligands. European Journal of Medicinal Chemistry. 132, 274-281. https://doi.org/10.1016/j.ejmech.2017.03.019



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