Journal article

Anticancer activity of a series of copper(II) complexes with tripodal ligands


Authors listJopp, M; Becker, J; Becker, S; Miska, A; Gandin, V; Marzano, C; Schindler, S

Publication year2017

Pages274-281

JournalEuropean Journal of Medicinal Chemistry

Volume number132

ISSN0223-5234

DOI Linkhttps://doi.org/10.1016/j.ejmech.2017.03.019

PublisherElsevier


Abstract
A series of copper(II) complexes with tripodal polypyridylamine ligands (derived from the parent ligand tris(2-pyridylmethyl)amine, tmpa) has been synthesized. Crystallographic characterization was possible for all complexes obtained. The copper(II) chloride complexes were investigated for their in vitro anticancer potential using human tumor cell lines containing examples of cervical, colon, ovarian cancers and melanoma. Some compounds showed a similar activity compared to that of cisplatin, however no systematic behavior could be observed.



Citation Styles

Harvard Citation styleJopp, M., Becker, J., Becker, S., Miska, A., Gandin, V., Marzano, C., et al. (2017) Anticancer activity of a series of copper(II) complexes with tripodal ligands, European Journal of Medicinal Chemistry, 132, pp. 274-281. https://doi.org/10.1016/j.ejmech.2017.03.019

APA Citation styleJopp, M., Becker, J., Becker, S., Miska, A., Gandin, V., Marzano, C., & Schindler, S. (2017). Anticancer activity of a series of copper(II) complexes with tripodal ligands. European Journal of Medicinal Chemistry. 132, 274-281. https://doi.org/10.1016/j.ejmech.2017.03.019


Last updated on 2025-21-05 at 15:14