Journalartikel

Interaction of hepatitis C virus with the type I interferon system


AutorenlisteWeber, F

Jahr der Veröffentlichung2007

Seiten4818-4823

ZeitschriftWorld Journal of Gastroenterology

Bandnummer13

Heftnummer36

ISSN1007-9327

eISSN2219-2840

DOI Linkhttps://doi.org/10.3748/wjg.v13.i36.4818

URLhttps://www.wjgnet.com/1007-9327/full/v13/i36/4818.htm

VerlagBaishideng Publishing Group


Abstract

Hepatitis C virus (HCV) needs to tightly manipulate host defences in order to establish infection. The innate immune response slows down viral replication by activating cytokines such as the type I interferons (IFN-alpha/beta), which trigger the synthesis of antiviral proteins and modulate the adaptive immune system. HCV has therefore developed a number of countermeasures to stay ahead of the IFN system. Here, I will attempt to summarize the current state of research regarding IFN responses against HCV and the viral escape strategies. Particular emphasis will be put on the newly discovered mechanisms HCV employs to avoid the induction of IFN in infected cells.




Zitierstile

Harvard-ZitierstilWeber, F. (2007) Interaction of hepatitis C virus with the type I interferon system, World Journal of Gastroenterology, 13(36), pp. 4818-4823. https://doi.org/10.3748/wjg.v13.i36.4818

APA-ZitierstilWeber, F. (2007). Interaction of hepatitis C virus with the type I interferon system. World Journal of Gastroenterology. 13(36), 4818-4823. https://doi.org/10.3748/wjg.v13.i36.4818


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