Journalartikel

Autorenliste: Neuser, F; Zorn, H; Berger, RG

Jahr der Veröffentlichung: 2000

Seiten: 560-568

Zeitschrift: A Journal of Biosciences

Bandnummer: 55

Heftnummer: 7-8

ISSN: 0939-5075

DOI Link: https://doi.org/10.1515/znc-2000-7-814

Verlag: De Gruyter

Abstract: 
The wild-type yeast strain Zygosaccharomyces bisporus CBS 702 produced alpha-hydroxyketones (acyloins) from amino acid precursors after transamination to the corresponding 2-oxo acids. The key enzyme of the subsequent decarboxylation and C-C bond forming reaction, pyruvate decarboxylase (PDC), was examined for its substrate- and stereo-specificity. A wide variety of saturated and unsaturated aliphatic and aromatic aldehydes was successfully converted to acyloins. 19 of the biotransformation products identified had not been reported as natural substances before. Product yields were strongly affected by substrate structure.

Harvard-Zitierstil: Neuser, F., Zorn, H. and Berger, R. (2000) Formation of aliphatic and aromatic α-hydroxy ketones by Zygosaccharomyces bisporus, Zeitschrift fur Naturforschung C, 55(7-8), pp. 560-568. https://doi.org/10.1515/znc-2000-7-814

APA-Zitierstil: Neuser, F., Zorn, H., & Berger, R. (2000). Formation of aliphatic and aromatic α-hydroxy ketones by Zygosaccharomyces bisporus. Zeitschrift fur Naturforschung C. 55(7-8), 560-568. https://doi.org/10.1515/znc-2000-7-814